James Murrough, MD Email James Murrough
- ASSISTANT PROFESSOR | Psychiatry
- ASSISTANT PROFESSOR | Neuroscience
- Hospital Affiliation
- The Mount Sinai Hospital
- New Office 212-241-7574212-241-7574
Key Words: depression, bipolar disorder, post traumatic stress disorder, psychopharmacology, antidepressants, functional neuroimaging
Financial & Billing Information
Please direct any detailed billing or financial inquires to the Mount Sinai Psychiatry billing customer service number at 212-659-8752.
Psychiatry, American Board of Psychiatry and Neurology
- Panic Disorder
- Post-Traumatic Stress Disorder
- Social Anxiety Disorder
- Specific Phobias
Mount Sinai Hospital
Pharmacologic attenuation of ketamine using nitroprusside
The purpose of this study is to investigate co-administration of ketamine with nitroprusside over two infusions as a means of potentially mitigating psychotomimetic effects of ketamine in depressed populations.
Intranasal Administration of Neuropeptide Y in PTSD
The purpose of this study is to evaluate the antidepressant and anti-anxiety effect of intranasal administration of neuropeptide Y (NPY) for patients with post-traumatic stress disorder (PTSD). NPY is not approved for the treatment of PTSD and is considered experimental in this s...
Murrough JW, Mathew SJ. Overcoming antidepressant treatment resistance: focus on glutamate. Modern Trends in Pharmacopsychiatry; 27.
Murrough JW, Mathew SJ. Neurochemical Imaging in Anxiety Disorders. Neuropsychiatric Imaging;.
Murrough JW, Mao X, Collins KA, Kelly C, Andrade G, Nestadt P, Levine SM, Mathew SJ, Shungu DC. Increased Ventricular Cerebrospinal Fluid Lactate in Chronic Fatigue Syndrome. Part II: Comparison with Major Depressive Disorder by 1H MRS at 3.0 Tesla. NMR Biomedicine 2010; 23: 643-650.
Murrough JW, Henry S, Hu J, Gallezot JD, Planeta-Wilson B, Neumaier JF, Neumeister A. Reduced ventral striatal/ventral pallidal serotonin(1B) receptor binding potential in major depressive disorder. Psychopharmacology (Berl) 2010 May;.
aan het Rot M, Collins KA, Murrough JW, Perez A, Reich DL, Charney DS, Mathew SJ. Safety and Efficacy of Repeated-Dose Intravenous Ketamine for Treatment-Resistant Depression. Biol Psychiatry 2010; 67: 139-145.
Mathew SJ, Murrough JW, aan het Rot M, Collins KA, Garakani A, Reich DL, Charney DS. Riluzole for Relapse Prevention Following Intravenous Ketamine in Treatment-Resistant Depression: A Pilot Randomized, Placebo-Controlled Study. Int J Neuropsychopharm 2010; 13: 71-82.
New AS, Fan J, Murrough JW, Liu X, Liebman RE, Guise KG, Tang CY, Charney DS. An Functional Magnetic Resonance Imaging Study of Deliberate Emotion Regulation in Resilience and Posttraumatic Stress Disorder. Biol. Psychiatry 2009; 66: 656-664.
Price RB, Shungu DC, Mao X, Nestadt P, Kelly C, Collins KA, Murrough JW, Charney DS, Mathew SJ. Amino Acid Neurotransmitters in the Occipital and Anterior Cingulate Cortices: Relationship to Treatment-Resistance in Major Depressive Disorder. Biol Psychiatry 2009; 65: 792-800.
Epstein J, Pan H, Kocsis JH, Yang Y, Butler T, Chusid J, Hochberg H, Murrough J, Strohmayer E, Stern E, Silbersweig DA. Lack of Ventral Striatal Response to Positive Stimuli in Depressed Versus Normal Subjects. Am J Psychiatry 2006; 163: 1784-1790.
Murrough JW, Boss-Williams KA, Emery MS, Bonsall RW, Weiss JM. Depletion of Brain Norepinephrine Does Not Reduce Spontaneous Ambulatory Activity of Rats in the Home Cage. Brain Res 2000; 883: 125-130.
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.
Below are financial relationships with industry reported by Dr. Murrough during 2017 and/or 2018. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
- Impel NeuroPharma
- ProPhase, LLC
Scientific Advisory Board:
- Genentech, Inc.
- Janssen Pharmaceuticals, Inc.
Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.
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