- PROFESSOR | Neurosurgery
- Hospital Affiliations
- Mount Sinai Beth Israel
- Mount Sinai St. Luke's and Mount Sinai West
- The Mount Sinai Hospital
- The Mount Sinai Hospital 212-241-3457212-241-3457
J Mocco, MD, MS, a cerebrovascular and endovascular neurosurgeon with clinical interests in stroke, brain aneurysms, subarachnoid hemorrhage, arteriovenous malformations, cavernous malformations, carotid artery stenosis, intracranial stenosis, and brain tumors, has joined Mount Sinai as Professor and Vice Chair for Education in the Department of Neurosurgery, and Director of the Cerebrovascular Center. Dr. Mocco was previously Associate Professor of Neurological Surgery, Radiology, and Radiological Sciences at Vanderbilt University Medical Center.
Dr. Mocco received his medical degree from the Columbia University College of Physicians and Surgeons. He completed his Master of Science in Biostatistics from the Mailman School of Public Health at Columbia University, a residency in Neurological Surgery from the Neurological Institute of New York and a fellowship in Endovascular Neurosurgery from the University of Buffalo.
Dr. Mocco has published more than 300 peer-reviewed publications, edited three texbooks on neurosurgical techniques, and runs numerous national and international clinical trials to improve the treatment of patients with cerebrovascular disease.
Dr. Mocco’s research interests focus on translational efforts to treat ischemic and hemorrhagic stroke.
- AVM surgery
- Acoustic Neuroma
- Acoustic Neuroma Removal
- Aneurysm Coiling
- Arnold-Chiari Syndrome
- Arteriovenous Malformations
- Atherectomy/Angioplasty Of Noncoronary Vessel
- Balloon Test Occlusion
- Brain Aneurysm
- Brain Metastasis
- Brain Tumor And Brain Cancer
- Brain, Spine Tumors
- Carotid Artery Endarterectomy
- Carotid Artery Stenosis
- Carotid Stenting
- Cavernous Malformations
- Chiari Malformation
- Computer Guided Crainiotomy
- Dural Arteriovenous Malformations
- Endovascular Embolization
- Facial Arteriovenous Malformations
- Facial Vascular Malformations
- Hemifacial Spasm
- Intracerebral Hemorrhage (ICH)
- Intracranial Stenting
- Lymphatic Malformations
- Mechanical Thrombectomy
- Microvascular Clipping
- Microvascular Occlusion
- Minimally invasive chiari decompression surgery
- Pediatric surgery
- Spinal Vascular Malformations
- Stereotactic Radiosurgery
- Subarachnoid Hemorrhage
- Transient Ischemic Attack
- Vascular Malformations
- Vein of Galen Malformations
- Venous Sampling
- Vertebral Stenosis
- Vertebroplasty And Kyphoplasty
- WADA Testing
Angiogenesis, Atherosclerosis, Blood-Brain Barrier, Brain, Brain Imaging, Endothelial Cells, Inflammation, Migration, Neuroscience, Stem Cells, Stroke, Transgenic Mice, Vascular Development
MD, Columbia University College of Physicians & Surgeons
New York Presbyterian-Columbia University Medical Center
Residency, Neurological Surg
University at Buffalo
The WEB® Intrasaccular Therapy Study (WEB-IT)
The purpose of this study is to demonstrate the safety and effectiveness of the WEB Aneurysm Embolization System for the treatment of intracranial wide-neck bifurcation aneurysms.
INVEST-REGISTRY: Minimally Invasive Endoscopic Surgical Treatment with Apollo in Patients with Brain Hemorrhage: A Prospective Multicenter Registry
The primary objective of this multicenter prospective registry is to provide additional safety, technical outcomes, and clinical outcomes data for minimally invasive endoscopic surgery (MIES) with Apollo for the evacuation of supratentorial brain hemorrhage in adult patients who ...
COAST: Coiling of Aneurysms Smaller Than 5mm With HyperSoft®
The primary objective of this post-marketing Study is to assess the clinical and imaging outcomes in the endovascular treatment of small (= 4.9 mm) intracranial aneurysms utilizing the HyperSoft® 3D (and HydroSoft® 3D, when commercially available) and HyperSoft® helical coils spe...
LARGE Aneurysm Randomized Trial: Flow Diversion Versus Traditional Endovascular Coiling
This is a prospective, randomized trial comparing endovascular coiling versus flow diversion for large and giant aneurysm treatment. The endovascular coiling used in this study are FDA-approved and in common use at institutions in this country and across the world. The flow diver...
POSITIVE: Perfusion Imaging Selection of Ischemic Stroke Patients for Endovascular Therapy
The primary objective of the POSITIVE study is to assess the safety and effectiveness of the Mechanical Thrombectomy (physically removing a blockage in a blood vessel) compared to best medical therapy (treatment with the best use of available medicines for this condition in strok...
Initial Clinical Experience with the Penumbra ACE 64 Catheter in the Treatment of Acute Ischemic Stroke: A Retrospective Registry
This retrospective study is being conducted in order to report on the initial clinical experience with the recently cleared ACE 64 catheter (Penumbra Inc., Alameda, CA, USA). This study aims to share operators' technical experiences with a type of catheter that was developed to i...
A Phase II, Randomized, Controlled Trial of Minimally Invasive Endoscopic Surgery with Apollo versus Medical Management in Supratentorial Intraparenchymal Hemorrhage
The primary aim of minimally invasive surgery (MIS) for supratentorial intracranial hemorrhage is to achieve an atraumatic evacuation of blood products from the brain to prevent the secondary injury that occurs after the initial bleed. The purpose of this Phase II randomized tria...
MISTIE III - A phase III, Randomized, Open Label, 500-Subject Clinical Trial of Minimally Invasive Surgery Plus rt-PA in the Treatment of Intraccebral Hemorrhage
MISTIE III will test a minimally invasive surgical procedure in which a hollow tube, called a catheter, is used to remove the blood clot from a bleed in the brain known as an intracerebral hemorrhage (ICH), and to administer a drug called rt-PA (recombinant tissue plasminogen act...
ADAPT: A Comparison of Direct Aspiration vs Stent Retriever As a First Approach
The primary objective of this randomized trial is to demonstrate the ADAPT approach is not inferior to that of conventional first-line stent retriever approach in Acute Ischemic Stroke (AIS) patients within 6 hours of symptom onset. The secondary objective is to demonstrate wheth...
Mocco J, Fiorella D, Fargen KM, Albuquerque F, Chen M, Gupta R, Hirsch JA, Linfante I, Mack W, Rai AT, Tarr RW. Endovascular therapy for acute ischemic stroke is indicated and evidence based: a position statement. Journal of neurointerventional surgery 2015 Feb; 7(2).
Ladner TR, Davis BJ, He L, Mawn LA, Mocco J. Transorbital superior ophthalmic vein sacrifice to preserve vision in ocular hypertension from aseptic cavernous sinus thrombosis. Journal of neurointerventional surgery 2014 Oct;.
Ladner TR, He L, Lakomkin N, Davis BJ, Cheng JS, Devin CJ, Mocco J. Minimizing bleeding complications in spinal tumor surgery with preoperative Onyx embolization via dual-lumen balloon catheter. Journal of neurointerventional surgery 2014 Dec;.
Fargen KM, Neal D, Fiorella DJ, Turk AS, Froehler M, Mocco J. A meta-analysis of prospective randomized controlled trials evaluating endovascular therapies for acute ischemic stroke. Journal of neurointerventional surgery 2015 Feb; 7(2).
Dababneh H, Bashir A, Hussain M, Guerrero WR, Morgan W, Khanna AY, Mocco JD. Endovascular treatment of tandem internal carotid and middle cerebral artery occlusions. Journal of vascular and interventional neurology 2014 Nov; 7(4).
Dababneh H, Hussain M, Guerrero WR, Xu J, Morgan W, Mocco J, Kirmani JF. . Journal of vascular and interventional neurology 2014 Nov; 7(4).
Ladner TR, Davis BJ, He L, Kirshner HS, Froehler MT, Mocco J. Complex decision-making in stroke: preoperative mechanical thrombectomy of septic embolus for emergency cardiac valve surgery. Journal of neurointerventional surgery 2014 Nov;.
Ladner TR, Davis BJ, He L, Kirshner HS, Froehler MT, Mocco J. Complex decision-making in stroke: preoperative mechanical thrombectomy of septic embolus for emergency cardiac valve surgery. BMJ case reports 2014; 2014.
Ladner TR, He L, Jordan LC, Cooper C, Froehler MT, Mocco J. Mechanical thrombectomy for acute stroke in childhood: how much does restricted diffusion matter?. Journal of neurointerventional surgery 2014 Nov;.
Velikina JV, Samsonov AA. Reconstruction of dynamic image series from undersampled MRI data using data-driven model consistency condition (MOCCO). Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2014 Nov;.
Ladner TR, He L, Jordan LC, Cooper C, Froehler MT, Mocco J. Mechanical thrombectomy for acute stroke in childhood: how much does restricted diffusion matter?. BMJ case reports 2014; 2014.
Linfante I, Mack W, Chen M, Rai A, Albuquerque F, Gupta R, Hirsch JA, Mocco J, Fiorella D, Tarr R. Best articles published in 2014 in Journal of NeuroInterventional Surgery. Journal of neurointerventional surgery 2014 Dec; 6(10).
Fargen KM, Mocco J, Gobin YP. The Lazarus Funnel: a blinded prospective randomized in vitro trial of a novel CE-marked thrombectomy assist device. Journal of neurointerventional surgery 2014 Nov;.
Gupta R, Rai AT, Hirsch JA, Linfante I, Mack W, Mocco J, Albuquerque F, Chen M, Fiorella D, Tarr RW. A research roadmap of future endovascular stroke trials. Journal of neurointerventional surgery 2015 Feb; 7(2).
Ladner TR, Davis BJ, He L, Mawn LA, Mocco J. Transorbital superior ophthalmic vein sacrifice to preserve vision in ocular hypertension from aseptic cavernous sinus thrombosis. BMJ case reports 2014; 2014.
King B, Vaziri S, Singla A, Fargen KM, Mocco J. Clinical and angiographic outcomes after stent-assisted coiling of cerebral aneurysms with Enterprise and Neuroform stents: a comparative analysis of the literature. Journal of neurointerventional surgery 2014 Oct;.
Turner R, Fiorella D, Mocco J, Frei D, Baxter B, Siddiqui A, Spiotta A, Chaudry I, Turk AS. Authors' reply. Journal of neurointerventional surgery 2014 Oct;.
Lin N, Brouillard AM, Keigher KM, Lopes DK, Binning MJ, Liebman KM, Veznedaroglu E, Magarik JA, Mocco J, Duckworth EA, Arthur AS, Ringer AJ, Snyder KV, Levy EI, Siddiqui AH. Utilization of Pipeline embolization device for treatment of ruptured intracranial aneurysms: US multicenter experience. Journal of neurointerventional surgery 2014 Sep;.
Goyal M, Almekhlafi M, Menon B, Hill M, Fargen K, Parsons M, Bang OY, Siddiqui A, Andersson T, Mendes V, Davalos A, Turk A, Mocco J, Campbell B, Nogueira R, Gupta R, Murphy S, Jovin T, Khatri P, Miao Z, Demchuk A, Broderick JP, Saver J. Challenges of acute endovascular stroke trials. Stroke; a journal of cerebral circulation 2014 Oct; 45(10).
Dababneh H, Bashir A, Guerrero WR, Wilson K, Hussain M, Misthal S, Morgan W, Peters K, Kirmani JF, Mocco J. Mean transit time on Aquilion ONE and its utilization in patients undergoing acute stroke intervention. Journal of vascular and interventional neurology 2014 Dec; 7(5).
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.
Below are financial relationships with industry reported by Dr. Mocco during 2016 and/or 2017. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
- Edge Therapeutics, Inc.
- Medina Medical, Inc.
Equity (Stock or stock options valued at greater than 5% ownership of a publicly traded company or equity of any value in a privately held company)
- Blockade Medical, LLC
- Lazarus Effect
- Medina Medical, Inc.
- Pulsar Healthcare
Other activities: Examples include, but are not limited to, committee participation, data safety monitoring board (DSMB) membership
- Medina Medical, Inc.
- Medtronic, Inc.
Scientific Advisory Board:
- Codman Neuro (DePuy Synthes)
Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.
Physicians who provide services at hospitals and facilities in the Mount Sinai Health System might not participate in the same health plans as those Mount Sinai hospitals and facilities (even if the physicians are employed or contracted by those hospitals or facilities).
Information regarding insurance participation and billing by this physician may be found on this page, and can also be obtained by contacting this provider directly. Because physicians insurance participation can change, the insurance information on this page may not always be up-to-date. Please contact this physician directly to obtain the most up-to-date insurance information.
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