Hearn Jay Cho, MD, PhD

Hearn Jay Cho, MD, PhD, is Associate Professor of Medicine (Hematology and Medical Oncology) at the Icahn School of Medicine at Mount Sinai.

Dr. Cho specializes in clinical care and research in multiple myeloma and related diseases. Dr. Cho received his medical degree and doctorate in Immunology at the Weill Medical College of Cornell University and did residency training in Internal Medicine at the University of California, San Diego. He was a clinical fellow in Hematology and Medical Oncology at Weill Medical College. In addition to his clinical training, Dr. Cho did post-doctoral training in Immunology at the University of California San Diego and Rockefeller University in New York. He has more than 20 years of experience as an investigator on clinical trials and actively manages patients on clinical trials for multiple myeloma and amyloidosis at Mount Sinai. Many of the trials involve collaborative translational research with cancer immunology groups at Mount Sinai and other institutions.

Dr. Cho’s research focuses on novel targeted therapies for multiple myeloma. His laboratory is developing combination strategies based on therapeutic tumor vaccines to elicit protective host immune responses against tumor cells, and is investigating the biochemical and molecular pathways of Melanoma Antigen Gene (MAGE) activity—MAGE is a family of cancer-associated genes the confer resistance to apoptosis in proliferating multiple myeloma cells.

Active in education, Dr. Cho mentors many graduate students, fellows in Hematology and Medical Oncology, fellows in Bone Marrow Transplantation, and postdoctoral research fellows.

Dr. Cho is a member of the Immunology Institute at Mount Sinai. He serves as a Multiple Myeloma Expert Reviewer for the Cancer Research Institute and is on the Board of Directors for Solving Kids Cancer. In addition to his academic duties at Mt. Sinai, Dr. Cho is the Chief Medical Officer of the Multiple Myeloma Research Foundation, where he oversees the clinical research program.