Effie M. Mitsis
- ASSOCIATE PROFESSOR Psychiatry
Yale University School of Medicine
Yale University School of Medicine
Ph.D., The Graduate Center of the City University of New York
Neuropsychology Doctoral Subprogram
Effie Mitsis, Ph.D. is an Assistant Professor of Psychiatry
at Mount Sinai School of Medicine in New York City. She is affiliated with the
James J. Peters VA Medical Center within the Department of Rehabilitation
Medicine as a neuropsychologist and is Vice Chair of the Institutional Review
Board. Dr. Mitsis received her doctorate in neuroscience and neuropsychology at
the Graduate School and University Center of the City University of New York
and conducted her dissertation research at Columbia University College of
Physicians and Surgeons. Dr. Mitsis completed one year pre-doctoral and
three-year postdoctoral fellowships in neuroimaging and neuropsychology at Yale
University School of Medicine and the Veterans Affairs Connecticut Healthcare
System, West Haven campus. Dr. Mitsis is a past board member of the Medical and
Scientific Advisory Council for the Connecticut chapter of the Alzheimer’s
At Mount Sinai, Dr. Mitsis conducts research in traumatic brain injury, aging and dementia within the renowned Alzheimer’s Disease Research Center. She is currently funded with an intramural grant to use PET and magnetic resonance imaging to investigate history of traumatic brain injury and depression as risk factors for earlier onset of Alzheimer’s disease in individuals with Mild Cognitive Impairment, typically referred to as MCI. MCI is considered the very early or prodromal stage of Alzheimer’s disease.
Dr. Mitsis’s current area of focus, for which she is extramurally funded through the Veterans Affairs administration as Principal Investigator, is mild traumatic brain injury associated with blast exposure in combat veterans returning from theaters of war in Iraq and Afghanistan. Dr. Mitsis is actively investigating the cognitive and neurobiological consequences of blast-exposure traumatic brain injury in these veterans, and is initiating studies to investigate the association between prior head injury, genetics, and earlier onset of dementia, such as that typically associated with Alzheimer’s disease. Her findings have been published in numerous peer-reviewed journals and she has written chapters addressing research advances in neuroimaging in Alzheimer’s disease and Mild Cognitive Impairment. She is a frequent invited speaker at forums addressing Alzheimer’s disease, mild cognitive impairment, and traumatic brain injury, and is a member of several national and international organizations for the imaging sciences and neuropsychology.
Mitsis EM, Jacobs D, Lou X, Andrews H, Andrews K, Sano M. Evaluating cognition in the elderly via telephone assessment. International Journal of Geriatric Psychiatry 2010; 25: 531-539.
Elder GA, Mitsis EM, Ahlers ST, Cristian A. Blast-induced mild traumatic brain injury. In: Riggio S, editor. Psychiatric Clinics of North America. New York, 2010.
Zhang J, Mitsis EM, Chu K, Newmark RE, Hazlett EA, Buchsbaum MS. SPM and cluster counting analysis of [18F]FDG-PET imaging in traumatic brain injury. Journal of Neurotrauma; 27: 35-49.
Mitsis EM, Estok KM, Staley JK, Bois F, Santosh L, MacAvoy MG, Seibyl JP, van Dyck CH. [123I]5-IA-85380 SPECT imaging of 2-nicotinic receptors in Alzheimer’s disease and mild cognitive impairment. Journal of Nuclear Medicine 2009; 50: 1455-1463.
Mitsis EM, Cosgrove KP, Staley JK, Frohlich E, van Dyck CH, Tamagnan GD, Estok KM, Seibyl JP, Bois F. Age-related decline in nicotinic receptor availability using [123I]5-IA-85380 SPECT. Neurobiology of Aging 2007;.
Mitsis EM, Bobinsky M, Brys M, Glodzik-Sobanska L, DeSanti S, Li Y, Kim B, De Leon MJ. Neuropathological and neuroimaging studies of the hippocampus in normal aging and in Alzheimer’s disease. In: Charney DS, Nestler EJ, editors. Neurobiology of Mental Illness, 3rd Edition. New York, Oxford University Press;.
Mitsis EM, Cosgrove KP, Staley JK, Frohlich E, van Dyck CH, Tamagnan GD, Estok KM, Seibyl JP, Bois F. [123I]5-IA-85380 SPECT Imaging of 2-Nicotinic Acetylcholine Receptor Availability in the Aging Human Brain. New York Academy of Sciences 2007; 1097: 168-170.
Cosgrove KP, Mitsis EM, Bois F, Perry E, Staley JK, Jatlow P, Tamagnan GD, Seibyl JP, van Dyck CH, Brenner E. [123I]5-IA-85380 SPECT Imaging of 2-Nicotinic Acetylcholine Receptors: Sex Differences in Receptor Availability in Healthy Non-Smokers versus Smokers. Journal of Nuclear Medicine 2007; 48: 1633-1640.
Mitsis EM, van Dyck CH. Neuroimaging in Alzheimer's Disease and Mild Cognitive Impairment. In: Research Progress in Alzheimer's Disease and Dementia
Neuroimaging in Alzheimer's Disease and Mild Cognitive Impairment. New York, Nova Science Publishers;.
Sano MC, Mitsis EM. Alzheimer's disease: Treatment and Management. In: Current Therapy in Neurologic Disease, 6th Edition
Alzheimer's disease: Treatment and Management. St. Louis, Mosby; pp308-312.
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.
Dr. Mitsis did not report having any of the following types of financial relationships with industry during 2012 and/or 2013: consulting, scientific advisory board, industry-sponsored lectures, service on Board of Directors, participation on industry-sponsored committees, equity ownership valued at greater than 5% of a publicly traded company or any value in a privately held company. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website at http://icahn.mssm.edu/about-us/services-and-resources/faculty-resources/handbooks-and-policies/faculty-handbook. Patients may wish to ask their physician about the activities they perform for companies.