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David Simpson

  • PROFESSOR Neurology, Neuromuscular Diseases
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  • Neuromuscular Medicine

  • Clinical Neurophysiology

  • Am Board of Electrodiagnostic Medicine

  • Neurology, American Board of Psychiatry and Neurology

Clinical Focus


  • MD, S.U.N.Y, Buffalo - School of Med & Biomed Science

  • Residency, Neurology
    New York Presbyterian - Weill Cornell Medical Center

  • Residency, Internal Medicine
    University Hospitals of Cleveland

  • Fellowship, Neurphysiology
    Massachusetts General Hospital


    David M. Simpson, MD, is currently Professor of Neurology at Mount Sinai School of Medicine in New York.  In addition, he is Director of the Clinical Neurophysiology Laboratories and Director of the Neuro-AIDS Program at Mount Sinai Hospital.

    Dr. Simpson received his medical degree from State University of New York (SUNY) at Buffalo School of Medicine. He completed an internship in Internal Medicine at University Hospitals of Cleveland, Case Western Reserve University in Cleveland, Ohio, and a residency in Neurology at Cornell University Medical Center in New York. He completed a fellowship in Clinical Neurophysiology at Massachusetts General Hospital, Harvard Medical School, in Boston, Massachusetts.

    An author of over 325 publications, Dr. Simpson is the principal investigator for many studies, including the treatment of neuropathic pain in patients with painful neuropathy and treatment of spasticity with botulinum toxin. Dr. Simpson recently led research studies demonstrating the safety and effectiveness of the high concentration capsaicin patch in the treatment of certain types of painful peripheral neuropathy.

    Dr. Simpson is a member of the American Neurological Association and the American Pain Society. He is a Fellow of the American Academy of Neurology, the American Academy of Neuromuscular and Electrodiagnostic Medicine, and the Royal College of Physicians. He is on the editorial board of AIDS Patient Care and Current HIV/AIDS Reports. 


  • 1997 -
    Royal College of Physicians and Surgeons of Canada Service Award

  • 1996 -
    Best Doctors in New York, New York Magazine

  • 1977 -
    Alpha Omega Alpha

  • 1976 -
    James A. Gibson Anatomical Society


Clifford DB, Vaida F, Kao YT, Franklin DR, Letendre SL, Collier AC, Marra CM, Gelman BB, McArthur JC, Morgello S, Simpson DM, Grant I, Heaton RK. Absence of neurocognitive effect of hepatitis C infection in HIV-coinfected people. Neurology 2015 Jan; 84(3).

Scelsa SN, Simpson D, Mcquistion H, Fineman A, Ault K, Reichler B. Clozapine-induced myotoxicity in patients with chronic psychotic disorders. Neurology 1996 Dec; 47(6): 1518-23.

Endo W, Santos FP, Simpson D, Maciel CD, Newland PL. Delayed mutual information infers patterns of synaptic connectivity in a proprioceptive neural network. Journal of computational neuroscience 2015 Apr; 38(2).

Scelsa SN, Simpson D, Reichler B, Dai M. Extraocular muscle involvement in Becker muscular dystrophy. Neurology 1996 Feb; 46(2): 564-6.

Heaton RK, Franklin DR, Deutsch R, Letendre SL, Ellis RJ, Casaletto K, Marquine MJ, Woods SP, Vaida F, Atkinson JH, Marcotte TD, McCutchan JA, Collier AC, Marra CM, Clifford DB, Gelman BB, Sacktor N, Morgello S, Simpson DM, Abramson I, Gamst A, Fennema-Notestine C, Smith DM, Grant I. Reply to haddow et Al. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2015 May; 60(9).

Reichler BD, Simpson DM. Peripheral neuropathies in the elderly. In: Tallis RC, Brocklehurst JC, Fillit H, editors. Brocklehurst's Textbook of Geriatrics and Gerontology. 5 London, Churchill Livingstone; 1998. pp612-625.

Wulff EA, Wang AK, Simpson DM. HIV-associated peripheral neuropathy: epidemiology, pathophysiology and treatment. Drugs 2000 Jun; 59(6): 1251-60.

Malvar J, Vaida F, Sanders CF, Atkinson JH, Bohannon W, Keltner J, Robinson-Papp J, Simpson DM, Marra CM, Clifford DB, Gelman B, Fan J, Grant I, Ellis RJ. Predictors of new-onset distal neuropathic pain in HIV-infected individuals in the era of combination antiretroviral therapy. Pain 2015 Apr; 156(4).

Wulff E, Simpson DM. Peripheral neuropathy associated with acquired immunodeficiency syndrome (AIDS)-related Burkitt's lymphoma. Muscle Nerve 2000 Nov; 23(11): 1764-6.

Robinson-Papp J, George MC, Dorfman D, Simpson DM. Barriers to Chronic Pain Measurement: A Qualitative Study of Patient Perspectives. Pain medicine (Malden, Mass.) 2015 Feb;.

Miyamoto K, Simpson D, Gurdon JB. Manipulation and In Vitro Maturation of Xenopus laevis Oocytes, Followed by Intracytoplasmic Sperm Injection, to Study Embryonic Development. Journal of visualized experiments : JoVE 2015;(96).

Reichler B, Scelsa SN, Simpson D. Hereditary neuropathy and vocal cord paralysis in a man with childhood diphtheria. Muscle Nerve 2000 Jan; 23(1): 132-7.

Sharma S, Mishra R, Simpson D, Wehman B, Colletti EJ, Deshmukh S, Datla SR, Balachandran K, Guo Y, Chen L, Siddiqui OT, Kaushal S, Kaushal S. Cardiosphere-derived cells from pediatric end-stage heart failure patients have enhanced functional activity due to the heat shock response regulating the secretome. Stem cells (Dayton, Ohio) 2015 Apr; 33(4).

Fisher AC, McCulloch DL, Borchert MS, Garcia-Filion P, Fink C, Eleuteri A, Simpson DM. Comparison of human expert and computer-automated systems using magnitude-squared coherence (MSC) and bootstrap distribution statistics for the interpretation of pattern electroretinograms (PERGs) in infants with optic nerve hypoplasia (ONH). Documenta ophthalmologica. Advances in ophthalmology 2015 Mar;.

Thompson DJ, Weissbecker I, Cash E, Simpson DM, Daup M, Sephton SE. Stress and cortisol in disaster evacuees: an exploratory study on associations with social protective factors. Applied psychophysiology and biofeedback 2015 Mar; 40(1).

Jost WH, Benecke R, Hauschke D, Jankovic J, Kaňovský P, Roggenkämper P, Simpson DM, Comella CL. Clinical and pharmacological properties of incobotulinumtoxinA and its use in neurological disorders. Drug design, development and therapy; 9.

Kaku M, Vinik A, Simpson DM. Pathways in the diagnosis and management of diabetic polyneuropathy. Current diabetes reports 2015 Jun; 15(6).

Industry Relationships

Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.

Below are financial relationships with industry reported by Dr. Simpson during 2014 and/or 2015. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.


  • Acorda Therapeutics Inc.; Allergan, Inc.; Astellas Pharma Inc.; Biogen Idec; Ipsen; Merz Pharmaceuticals, LLC

Scientific Advisory Board:

  • Acorda Therapeutics Inc.; Allergan, Inc.

Industry-Sponsored Lectures: MSSM faculty occasionally give lectures at events sponsored by industry, but only if the events are free of any marketing purpose.

  • Allergan, Inc.

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.

Insurance Information

Physicians who provide services at hospitals and facilities in the Mount Sinai Health System might not participate in the same health plans as those Mount Sinai hospitals and facilities (even if the physicians are employed or contracted by those hospitals or facilities).

Information regarding insurance participation and billing by this physician may be found on this page, and can also be obtained by contacting this provider directly. Because physicians insurance participation can change, the insurance information on this page may not always be up-to-date. Please contact this physician directly to obtain the most up-to-date insurance information.

Insurance and health plan networks that the various Mount Sinai Health System hospitals and facilities participate in can be found on the Mount Sinai Health System website.

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