Photo of Constantinos Hadjipanayis
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Constantinos G Hadjipanayis, MD, PhD
Neurosurgery
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    • Positions
    • SITE CHAIR, DEPARTMENT OF NEUROSURGERY, MOUNT SINAI BETH ISRAEL
    • PROFESSOR | Neurosurgery
    • PROFESSOR | Oncological Sciences
    • Specialty
    • Neurosurgery
    • Languages
    • English
    • Greek
    • Hospital Affiliations
    • Mount Sinai St. Luke's and Mount Sinai West
    • The Mount Sinai Hospital
    • Mount Sinai Beth Israel
    • New York Eye and Ear Infirmary of Mount Sinai
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10 Union Square East 5th Floor, Suite 5E
New York, NY 10003
Phone: 212-844-6922
A renowned surgical neuro-oncologist Constantinos (Costas) G. Hadjipanayis, is Professor and Chair of the Department of Neurosurgery at Mount Sinai Beth Israel in New York City, New York. He is also Director of Neurosurgical Oncology for the Mount Sinai Health System and Director of the Brain Tumor Nanotechnology Laboratory in the Tisch Cancer Institute.

Both as a neurosurgeon and an NIH-funded scientist, Dr. Hadjipanayis is recognized as a neuro-oncology pioneer for driving advancements in the therapy and surgical management of brain tumors. He is also an internationally recognized expert in minimally invasive, neuro-endoscopic procedures to treat disorders in the brain.

Dr. Hadjipanayis’ interests include surgery and experimental therapeutics for malignant brain tumors, neuro-endoscopy for pituitary tumors and especially colloid cysts, for which his published experience is one of the largest reported. In addition he performs microsurgery and radiosurgery for tumors of the skull base and spinal cord.

In addition to his clinical interests, Dr. Hadjipanayis leads multiple cooperative group- and industry-sponsored clinical trials for patients with malignant brain tumors. He was the first in North America to perform approved fluorescence-guided surgery for malignant gliomas with the use of an orphan drug known as Gliolan that can light up tumors in the operating room. He is the lead principal investigator and an IND holder for Gliolan in the USA. He has studied novel targeted therapies for malignant brain tumors such as cancer stem cells delivered by convection-enhanced delivery. He completed a unique animal trial of brain tumors using a magnetic nanoparticle therapeutic agent developed in his laboratory that can target brain tumor cells and can also be seen by MRI.

Dr. Hadjipanayis received his medical degree from Jefferson Medical College in Philadelphia. He completed his internship and residency in neurosurgery at the University of Pittsburgh School of Medicine, simultaneously obtaining his PhD in the Department of Molecular Genetics and Biochemistry. He pursued further advanced training in awake craniotomy techniques and intraoperative cortical/subcortical mapping at the University of California San Francisco (UCSF).

Prior to joining Mount Sinai, Dr. Hadjipanayis was an Associate professor in the Department of Neurosurgery at Emory University School of Medicine, Chief of Neurosurgery at Emory University Hospital Midtown, and Director of the Winship Brain Tumor Center of Emory. He was also the President of the Georgia Neurosurgical Society and the Southeastern Brain Tumor Foundation.

Dr. Hadjipanayis is a member of the American Association of Cancer Research (AACR), American Association of Neurological Surgeons (AANS), Congress of Neurological Surgeons (CNS), AANS/CNS Section on Tumor, and the Society of Neuro-Oncology. He previously served as the President of the non-profit Southeastern BrainTumor Foundation (SBTF) and the Georgia Neurosurgical Society (GNS).

Dr. Hadjipanayis has been designated a Georgia Cancer Coalition Distinguished Scholar. He has received multiple awards including the American Brain Tumor Association (ABTA) Young Investigator Award, American Academy of Neurological Surgery Award, Atlanta Business Chronicle Health Care Hero Award, Brain Tumor Biotech Young Innovator Award, Southeastern Brain Tumor Foundation Philip Jory Award, and a Robbins Scholar Award from the Winship Cancer Institute of Emory University. He was also the Professor M. Natarajan Memorial Orator at the Madurai Neurosurgical Academy in Chennai, India.

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Certification

Neurological Surgery

Clinical Focus

  • 3D Simulation
  • Acoustic Neuroma
  • Acoustic Neuroma Removal
  • Acromegaly
  • Adenomas
  • Arnold-Chiari Syndrome
  • Astrocytoma
  • Biopsy
  • Brain Metastasis
  • Brain Tumor And Brain Cancer
  • Brain Tumor And Brain Cancer-Adult
  • Brain Tumors
  • Brain, Spine Tumors
  • Cavernous Malformations
  • Cerebrospinal Fluid Leak
  • Chiari Malformation
  • Chondrosarcoma
  • Chordoma
  • Computer Guided Crainiotomy
  • Craniopharyngioma
  • Craniotomy
  • Cushing's Syndrome
  • Epidermal Cyst
  • Galactorrhea
  • Glioblastoma
  • Glioblastoma Multiforme
  • Hemangioblastoma
  • Hemangioma
  • Hemangiomas
  • Hemifacial Spasm
  • Hydrocephalus
  • Hypopituitarism
  • Intracerebral Hemorrhage (ICH)
  • Melanoma
  • Meningioma
  • Metastases
  • Neuro-Oncology
  • Neuroendoscopy
  • Neurofibromatosis
  • Neurosurgical Oncology
  • Oligodendroglioma
  • Ophthalmic Tumors
  • Panhypopituitarism
  • Pituitary Adenoma
  • Pituitary Diseases
  • Primary Central Nervous System Lymphoma
  • Skull Base Tumor/Cancer
  • Skull Base Tumors
  • Spinal Cord Tumors
  • Spinal Stenosis
  • Stereotactic Radiosurgery
  • Subdural Hematoma
  • Trigeminal Neuralgia

Research Topics

Brain, Brain Imaging, Cancer, Nanotechnology

Education

MD, Jefferson Medical College

Internship, General Surgery
University of Pittsburgh Medical Center

Residency, Neurosurgery
University of Pittsburgh Medical Center

Languages

English, Greek