Fellowship, Princeton University
PhD, Rutgers University
Fellowship, Mount Sinai School of Medicine
Biophysics and Systems Pharmacology [BSP]
Lifetime Achievement Award
Research Society on Alcoholism
Mount Sinai Faculty Council Award for Academic Excellence
Ronald G. Thurman Lectureship Award
University of North Carolina
Outstanding Faculty Achievement Award Basic Sciences
Excellence in Teaching Medical School
Hong F, Liu X, Ward SS, Xiong H, Cederbaum AI, Lu Y. Absence of cytochrome P450 2A5 enhances alcohol-induced liver injury in mice. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2015 Mar;.
Cederbaum AI. Molecular mechanisms of the microsomal mixed function oxidases and biological and pathological implications. Redox biology 2015; 4.
Cederbaum AI, Lu Y, Wang X, Wu D. Synergistic toxic interactions between CYP2E1, LPS/TNFα, and JNK/p38 MAP kinase and their implications in alcohol-induced liver injury. Advances in experimental medicine and biology 2015; 815.
Cederbaum AI. Methodology to assay CYP2E1 mixed function oxidase catalytic activity and its induction. Redox biology 2014 Oct; 2C.
Liu H, Lou G, Li C, Wang X, Cederbaum AI, Gan L, Xie B. HBx inhibits CYP2E1 gene expression via downregulating HNF4α in human hepatoma cells. PloS one 2014; 9(9).
Wang Y, Kou Y, Wang X, Cederbaum A, Wang R. Multifactorial comparative proteomic study of cytochrome P450 2E1 function in chronic alcohol administration. PloS one 2014; 9(3).
Yang L, Rozenfeld R, Wu D, Devi LA, Zhang Z, Cederbaum A. Cannabidiol protects liver from binge alcohol-induced steatosis by mechanisms including inhibition of oxidative stress and increase in autophagy. Free radical biology & medicine 2014 Mar; 68.
Wu D, Cederbaum AI. Inhibition of autophagy promotes CYP2E1-dependent toxicity in HepG2 cells via elevated oxidative stress, mitochondria dysfunction and activation of p38 and JNK MAPK. Redox Biology 2013 Nov; 1(1): 552-65.
Lu Y, Ward SC, Cederbaum AI. Nicotine enhances ethanol-induced fat accumulation and collagen deposition but not inflammation in mouse liver. Alcohol 2013 Aug; 47(5): 353-7.
Wang X, Wu D, Yang L, Gan L, Cederbaum AI. Cytochrome P450 2E1 potentiates ethanol induction of hypoxia and HIF-1α in vivo. Free Radical Biology and Medicine 2013 Oct; 63: 175-86.
Cederbaum AI. Nrf2 and Antioxidant Defense Against CYP2E1 Toxicity. Sub-cellular Biochemistry 2013; 67: 105-30.
Wu D, Wang X, Zhou R, Yang L, Cederbaum AI. Alcohol steatosis and cytotoxicity: the role of cytochrome P4502E1 and autophagy. Free Radical Biology and Medicine 2012 Sep; 53(6): 1346-57.
Yang L, Wu D, Wang X, Cederbaum AI. Cytochrome P4502E1, oxidative stress, JNK, and autophagy in acute alcohol-induced fatty liver. Free Radical Biology and Medicine 2012 Sep; 53(5): 1170-80.
Lu Y, Zhang XH, Cederbaum AI. Ethanol induction of CYP2A5: role of CYP2E1-ROS-Nrf2 pathway. Toxicological Sciences 2012 Aug; 128(2): 427-38.
Cederbaum AI, Yang L, Wang X, Wu D. CYP2E1 Sensitizes the Liver to LPS- and TNF α-Induced Toxicity via Elevated Oxidative and Nitrosative Stress and Activation of ASK-1 and JNK Mitogen-Activated Kinases. International Journal of Hepatology 2012; 2012.
Yang L, Wu D, Wang X, Cederbaum AI. Depletion of cytosolic or mitochondrial thioredoxin increases CYP2E1-induced oxidative stress via an ASK-1-JNK1 pathway in HepG2 cells. Free Radical Biology and Medicine 2011 Jul; 51(1): 185-96.
Lu Y, Wu D, Wang X, Ward SC, Cederbaum AI. Ethanol induction of CYP2A5: permissive role for CYP2E1. Drug Metabolism and Disposition 2011 Feb; 39(2): 330-6.
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.
Dr.Cederbaum did not report having any of the following types of financial relationships with industry during 2015 and/or 2016: consulting, scientific advisory board, industry-sponsored lectures, service on Board of Directors, participation on industry-sponsored committees, equity ownership valued at greater than 5% of a publicly traded company or any value in a privately held company. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.
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