Vascular Research at Mount Sinai
Mount Sinai is committed to maintaining the utmost excellence in all aspects of patient care. As a means to enriching the current clinical practices and expanding future practices to encompass highly skilled, cutting-edge techniques, and scientific knowledge, our interdisciplinary team of vascular surgeons, vascular medicine and interventional specialists, and cardiologists are dedicated to pursuing research activities specific to a plethora of topics related to diagnosing and treating vascular conditions.
From the laboratory to the patient care settings, research activities ranging from sponsored clinical trials and federally-funded grants to investigator-initiated studies, each maintain a crucial role in the short and long-term practices and overall vision of Mount Sinai.
Our investigators are studying the following areas in order to improve the detection, treatment, and clinical outcomes of vascular diseases:
- Exploring trends in aneurysm morphology, such as angulation and tortuosity, to determine how these morphologies are correlated with varying patient clinical outcomes; recent morphology research efforts have centered on abdominal aortic aneurysms and thoracic aortic aneurysms.
- Examining the genetic basis for abdominal aortic aneurysm disease to determine whether underlying risk or causative factors impact a patient’s risks of diagnosis
- Assessing the efficacy of surgical procedures specific to endovascular aneurysm repair, focusing on which factors – such as the anatomical features of the aneurysm, comorbidities, and pre-operative adjunctive maneuvers, significantly impact a patient’s post-operative clinical outcomes
Fibromuscular Dysplasia Research
- Investigating the genetic causes of fibromuscular dysplasia, using fibroblasts created from skin biopsies
- Maintaining a national registry of fibromuscular dysplasia patients and investigating the natural history and progression of this vascular condition
- Examining how biologic and genetic aspects of fibromuscular dysplasia translate into clinical manifestations
- Exploring the similarities and differences in the cardiovascular disease risk factor profile of people with fibromuscular dysplasia and those without this condition, as it relates to the amount of atherosclerosis
Hemodialysis Access Research
- Compiling, tracking, and analyzing data surrounding vascular access creation for hemodialysis patients (creation of an arteriovenous graft or arteriovenous fistula for dialysis access)
- Assessing the impact that different variables play on long-term clinical outcomes for patients with vascular access creation for hemodialysis
- Evaluating the efficacy of investigational techniques to reduce the incidence of clinical complications associated with vascular access creation procedures
Peripheral Artery Disease Research
- Investigating new therapies in patients with peripheral artery disease, especially the cardiovascular effects of these new compounds
Venous Obstruction and Ulceration Research
- Analyzing clinical outcomes data for patients undergoing intravascular ultrasound imaging as compared to multi-planar venography, specifically relating to recognition of the venous obstruction or area of compression resulting in the change in treatment (which can result in venous ulceration)
Division of Vascular and Endovascular Surgery
Vascular Interventions – Cardiac Cath Lab