Radionuclide - gallbladder; Gallbladder scan; Biliary scan; Cholescintigraphy: HIDA; Hepatobiliary nuclear imaging scan
Gallbladder radionuclide scan is a test that uses radioactive material to check gallbladder function. It is also used to look for bile duct blockage or leak.
The health care provider will inject a radioactive chemical called a gamma emitting tracer into a vein. This material collects mostly in the liver. It will then flow with bile into the gallbladder and then the duodenum or small intestine.
For the test:
If the provider cannot see the gallbladder after certain amount of time, you may be given a small amount of morphine. This can help the radionuclide get into the gallbladder. The morphine may cause you to feel tired after the exam.
In some cases, you may be given a medicine during this test to see how well your gallbladder squeezes (contracts).
You need to eat something within a day of the test. However, you must stop eating or drinking 4 hours before the test starts.
You will feel a sharp prick from the needle when the tracer is injected into the vein. The site may be sore after the injection. There is normally no pain during the scan.
This test is very good for detecting a sudden infection of the gallbladder or blockage of a bile duct. It is also helpful in determining whether there is rejection of a transplanted liver or a leak after the gallbladder has been surgically removed.
The test can also be used to detect long-term gallbladder problems.
Abnormal results may be due to:
There is a small risk to pregnant or nursing mothers. Unless it is absolutely necessary, the scan will be delayed until you are no longer pregnant or nursing.
The amount of radiation is small (less than that of a regular x-ray). It is almost all gone from the body within 1 or 2 days. Your risk from radiation may increase if you have a lot of scans.
Most of the time, this test is done only if a person has sudden pain that may be from gallbladder disease or gallstones. For this reason, some people may need urgent treatment based on the test results.
This test is combined with other imaging (such as CT or ultrasound). After the gallbladder scan, the person may be prepared for surgery, if needed.
Afdahl NH. Diseases of the gall bladder and bile ducts In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine. 24th ed. Philadelphia, PA: Elsevier Saunders; 2011:chap 158.
Wang DQH, Afdahl NH. Gallstone disease. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 9th ed. Philadelphia, PA: Elsevier Saunders; 2010:chap 65.
Last reviewed on: 1/18/2015
Reviewed by: Jason Levy, MD, Northside Radiology Associates, Atlanta, GA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.