NF2; Bilateral acoustic neurofibromatosis; Central bilateral acoustic NF
Neurofibromatosis 2 (NF2) is a disorder in which tumors form on the nerves of the brain and spine (the central nervous system). It is passed down (inherited) in families.
Although it has a similar name to neurofibromatosis type 1, it is a different and separate condition.
NF2 can be passed down through families in an autosomal dominant pattern. This means that if 1 parent has NF2, any child of that parent has a 50% chance of inheriting the condition.
The main risk factor is having a family history of the condition.
Symptoms of NF2 include:
Signs of NF2 include:
Acoustic tumors can be observed, or treated with surgery or radiation.
People with this disorder may benefit from genetic counseling.
People with NF2 should be regularly evaluated with these tests:
A support group can be helpful for emotional support and for giving and receiving practical advice. For information and support, visit
Evans DG. Neurofibromatosis 2. GeneReviews. Seattle, WA; University of Washington; 2011:8.
Sahin M. Neurocutaneous syndromes. In: Kliegman RM, Stanton BF, St Geme III JW, Schor NF, eds. Nelson Textbook of Pediatrics. 20th ed. Philadelphia, PA: Elsevier; 2016:chap 596.
Last reviewed on: 10/27/2015
Reviewed by: Chad Haldeman-Englert, MD, FACMG, Fullerton Genetics Center, Asheville, NC. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.