Stromal tumor; Gonadal stromal tumor; Sex cord tumor; Androblastoma
This is a rare tumor. It accounts for less than 0.5% of all ovarian tumors.
These tumors are found in women of all age groups, but are most common in young women.
This tumor releases male hormones, which cause the following symptoms in women:
The following tests are used to diagnose the condition:
Surgery to remove the tumor is the main treatment. If the cancer has spread, chemotherapy or radiation therapy may be considered.
The outcome of this disease depends on whether it has spread, and whether surgery can completely remove the tumor.
Arrhenoblastoma has a low chance of spreading. If the tumor is found early, the cure rate can be very good.
Complications may include:
Call your health care provider if you are a woman and have masculine symptoms. Also call if you feel a lump in your lower belly area.
There is no good screening test. Regular gynecologic exams and recognizing masculine symptoms may help detect the disease.
Bulun SE. The physiology and pathology of the female reproductive axis. In: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, eds. Williams Textbook of Endocrinology. 13th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 17.
Lobo RA. Hyperandrogenism. In: Lentz GM, Lobo RA, Gershenson DM, Katz VL, eds. Comprehensive Gynecology. 6th ed. Philadelphia, PA: Elsevier Mosby; 2012:chap 40.
Last reviewed on: 2/12/2016
Reviewed by: Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.