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Full/Part Time: Full Time
Location/Affiliates: Mount Sinai Medical Center (Manhattan)
Department: 031 - Hematology/Oncology
Requisition Number: PD12-1392078
Postdoctoral Opportunity in Regulation of Hematopoietic Development
A postdoctoral position is available to study mechanisms underlying the development of hematopoietic cells during mammalian development. We are taking a number of molecular, cellular and genetic approaches to understand possible signals and transcription factors involved in specification of mesoderm to hematopoietic fates and in mechanisms underlying erythroid (red blood cell) maturation at different stages of ontogeny. Red blood cells undergo a number of distinctive cellular and molecular changes, including redistribution of proteins on the cell surface, chromatin condensation, and enucleation. We are interested in studying these events in development and disease. This work takes advantage of unique transgenic mouse and embryonic stem cell (ES cell) lines developed in our laboratory as well as a genome-wide transcriptional profiling study of embryonic red blood cells at 6 sequential stages of development.
The ideal candidate has an MD and/or PhD degree, a strong background in
molecular, cellular and developmental biology, and demonstrated productivity in the laboratory. Experience with mammalian cell culture or with mouse models highly desirable. Preference will be given to applicants seeking their first postdoctoral position.
Mount Sinai Medical Center is an equal opportunity/affirmative action employer. We recognize the power and importance of a diverse employee population and strongly encourage applicants with various experiences and backgrounds. Mount Sinai Medical Center--An EEO/AA-D/V Employer.