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Associate Researcher II
Full/Part Time: Full Time
Location/Affiliates: Mount Sinai Medical Center (Manhattan)
Department: 867 - Neurosciences
Requisition Number: 14-1621238
Associate Researcher II
Our research focuses on identifying the epigenetic basis of neurodegenerative and psychiatric disorders. We study how miRNAs and histone modifying enzymes contribute to the establishment and maintenance of neuronal identity and specialized functions. We are particularly interested in understanding the epigenetic mechanisms of cellular plasticity and its role in regulation of microglia-neuron communication. One of the major focuses of our research lies in the development of animal models of human neurological disease associated with abnormal function of epigenetic regulators of different types. Using pioneering technologies including cell type specific analysis of mRNAs, miRNAs and chromatin modifications in neurons in vivo, our research aims at understanding the mechanism of neurological disorders and at their potential treatment by targeting the neuronal epigenome. The Research Assistant will contribute towards our research in the field of brain epigenetics. Duties will include performing a variety of molecular biology techniques, such as mammalian cell culture, isolation of DNA, RNA and protein, Western Blotting, PCR and molecular cloning. In addition, the candidate will provide support in maintaining and analyzing transgenic mouse lines used in our studies. This will include genotyping, tissue sectioning, immunostaining and behavioral analyses.
JOB QUALIFICATIONS Applicants must have either a Bachelors of Master's degree with a background in neuroscience, molecular and cellular biology, neurodegenerative disorders or related field desirable. Basic experience in general laboratory techniques and willingness to work with transgenic animals required. Basic computer skills required.
Mount Sinai Medical Center is an equal opportunity/affirmative action employer. We recognize the power and importance of a diverse employee population and strongly encourage applicants with various experiences and backgrounds. Mount Sinai Medical Center--An EEO/AA-D/V Employer.