• Press Release

Mount Sinai Health System Launches Collaboration With the Regeneron Genetics Center

  • New York, NY
  • (November 09, 2016)

Mount Sinai Health System today announced it will extend its work with Regeneron Pharmaceuticals, Inc. through a collaboration with its wholly owned subsidiary, the Regeneron Genetics Center (RGC), to perform whole exome sequencing on 33,000 DNA and plasma samples housed in Mount Sinai’s BioMe™ Biobank, one of the first biobank repositories in the country to link DNA sequencing data to clinical information stored within the electronic medical record (EMR).  

“The Mount Sinai BioMe Biobank is distinguished by its rich diversity in patient populations linked to electronic medical records,” said Judy Cho, MD, Ward-Coleman Professor of Translational Genetics and Medicine and Director of The Charles Bronfman Institute for Personalized Medicine at the Icahn School of Medicine at Mount Sinai. “We are extremely pleased to enter into this collaboration with the RGC to develop high-quality sequence data from the BioMe cohort. This partnership provides an important means of more effectively personalizing medical care throughout the Mount Sinai Health System.”

The BioMe Biobank constitutes one of the largest collection of samples collections in the United States that can be used for the analysis and sequencing of genetic material and comparison to long-term health outcomes. The RGC will perform whole exome sequencing to generate de-identified genomic data and analyze that data alongside EMRs, in order to discover actionable insights about human diseases that may be applied to drug discovery and development. The size and scope of the study, one of the largest of its kind, are meant to allow greater precision in identifying and validating the associations between genes and human disease, and potentially pinpointing more effective therapies for patients.

“We are excited to work with Regeneron, global leaders in advanced sequencing technology, analysis and translational medicine,” said Erik Lium, PhD, Senior Vice President of Mount Sinai Innovation Partners. “This has the potential to dramatically change outcomes, ensuring a deeper understanding of disease and paving the way for therapeutic discoveries.”

“This marks Regeneron’s second recent collaboration with Mount Sinai, an important neighbor in the New York bioscience community,” said Alan Shuldiner, MD, Vice President and Co-Head of the Regeneron Genetics Center. “The pairing of Mount Sinai’s clinical excellence and Regeneron’s expertise in genetics-based research and therapeutic development holds enormous promise for discoveries that could ultimately benefit patients around the globe.”

About the Mount Sinai Health System

The Mount Sinai Health System is an integrated health system committed to providing distinguished care, conducting transformative research, and advancing biomedical education. Structured around seven hospital campuses and a single medical school, the Health System has an extensive ambulatory network and a range of inpatient and outpatient services—from community-based facilities to tertiary and quaternary care.

The System includes approximately 7,100 primary and specialty care physicians; 12 joint-venture ambulatory surgery centers; more than 140 ambulatory practices throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and 31 affiliated community health centers. Physicians are affiliated with the renowned Icahn School of Medicine at Mount Sinai, which is ranked among the highest in the nation in National Institutes of Health funding per investigator. The Mount Sinai Hospital is in the "Honor Roll" of best hospitals in America, ranked No. 15 nationally in the 2016-2017 "Best Hospitals" issue of U.S. News & World Report. The Mount Sinai Hospital is also ranked as one of the nation's top 20 hospitals in Geriatrics, Gastroenterology/GI Surgery, Cardiology/Heart Surgery, Diabetes/Endocrinology, Nephrology, Neurology/Neurosurgery, and Ear, Nose & Throat, and is in the top 50 in four other specialties. New York Eye and Ear Infirmary of Mount Sinai is ranked No. 10 nationally for Ophthalmology, while Mount Sinai Beth Israel, Mount Sinai St. Luke's, and Mount Sinai West are ranked regionally. Mount Sinai's Kravis Children's Hospital is ranked in seven out of ten pediatric specialties by U.S. News & World Report in "Best Children's Hospitals."

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