Ivanhoe - Dr. Giulio Maria Pasinetti: “Possible Alzheimer's Vaccine”
Alzheimer’s disease (AD) is the leading cause of dementia in the elderly and is an incurable disease that affects more than five million people. Now intravenous human immunoglobulin (IVIG) treatment is currently being explored for uses other than immunotherapy, including AD. Recent studies by Dr. Giulio Maria Pasinetti, Saunders Family Chair and Professor in Neurology and Psychiatry at Mount Sinai School of Medicine, demonstrate that the diverse outcomes in AD studies of IVIG may be due to differences in temporal administration and administered doses. “This experimental observation provides a rational basis for rectifying the inconsistency of study outcomes in Alzheimer's disease clinical trials with IVIG. We now have the much needed information supporting the potential application of slow release of immunoglobulin’s delivered subcutaneously to delay the onset of Alzheimer's disease, even at pre-symptomatic stages of the disease," said Dr. Pasinetti. Learn more
About the Mount Sinai Health System
Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 47,000 employees working across seven hospitals, more than 400 outpatient practices, more than 600 research and clinical labs, a school of nursing, and leading schools of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time—discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high-quality care to all who need it.
Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive health care from conception through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics while keeping patients’ medical and emotional needs at the center of all treatment. The Health System includes more than 6,400 primary and specialty care physicians and 10 free-standing joint-venture centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida. Hospitals within the System are consistently ranked by Newsweek’s® “The World’s Best Smart Hospitals,” “Best in State Hospitals,” “World’s Best Hospitals,” and “Best Specialty Hospitals” and by U.S. News & World Report's® “Best Hospitals” and “Best Children’s Hospitals.” The Mount Sinai Hospital is on the U.S. News & World Report® “Best Hospitals” Honor Roll for 2025-2026.
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