News-Medical.net - "FSH-Specific Polyclonal Antibody Might Offer More Effective Way To Prevent Osteoporosis"
A new study suggests that a polyclonal antibody that blocks follicle-stimulating hormone (FSH) in mice without ovaries might offer a more effective way to prevent or arrest osteoporosis than currently available treatments. Mount Sinai researchers used a mouse model of menopause to show that an injection of a polyclonal antipeptide antibody enhances bone regeneration by simultaneously slowing bone destruction and building bone. "Bone loss in women begins very early, at least two to three years before a woman's last period and within eight to ten years, a woman will lose 50 percent of her lifetime bone loss," says the study's senior investigator, Mone Zaidi, MD, Professor of Medicine and of Structural and Chemical Biology, at Mount Sinai School of Medicine. "It occurs painlessly, without notice up to a point where women fracture." Learn more