• News

"Mount Sinai Researchers Crowdsource Gene Expression Data for Drug and Target Discovery"

  • HIT Consultant
  • New York, NY
  • (October 10, 2016)

Researchers at the Icahn School of Medicine at Mount Sinai have crowdsourced the annotation and analysis of a large number of gene expression profiles from the National Center for Biotechnology Information’s (NCBI) Gene Expression Omnibus (GEO). For the project, more than 70 volunteers from 25 countries helped Mount Sinai researchers analyze the data, enabling the identification of new associations between genes, diseases, and drugs – something that a smaller number of unaided researchers, or an automated computer program, would not be able to achieve. “There is an incredible amount of data stored in these databases, but much of it has not been fully explored,” said Avi Ma’ayan, PhD, director of the Mount Sinai Center for Bioinformatics. “By utilizing volunteers, so called ‘citizen-scientists,’ we were able to bring a much greater scale of human curation and quality control than we could have performed alone. By combining that human touch with automated programs, we could process much more data than would have been otherwise possible.” Learn more. 

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