Publications

1. Roboz, J. Introduction to Mass Spectrometry: Instrumentation and Techniques. Textbook, Wiley-Interscience, NY, 1968, 539 pages. Reprinted: 1979. Selected as “Classic Works in Mass Spectrometry”, Vol. 3, American Society Mass Spectrometry, 2000.
2. Roboz, J. Mass Spectrometry in Cancer Research, Textbook, 554 pages, CRC Press; 2002. Second edition to be published in 2007. Award from the British Medical Association: “Commended in the Basic and Clinical Sciences category of the 2003 BMA Medical Book Competition”. 
3. Roboz, J., Chahinian, A.P., Holland, J.F., Silides, D. and Szrajer L. Early diagnosis and monitoring of transplanted human malignant mesothelioma by serum hyaluronic acid. J. Natl. Cancer Inst. 81, 924-928 (1989). 
4. Roboz, J., Diagnosis and monitoring of disseminated candidiasis based on blood/urine D/L arabinitol ratios. Chirality, 6, 51-57 (1994). 
5. Roboz, J.,Yu, Q., Meng, A. and van Soest, R. On-line buffer removal and fraction selection in gradient capillary HPLC prior to electrospray mass spectrometry of peptides and proteins. Rapid Commun. Mass Spectrom. 8, 621-626 (1994). 
6. Jiang, J.D., Hong, K., Roboz, J., Strauchen, J., Weisz, I., Holland, J.F. and Bekesi, J.G. Inhibition of microtubule assembly in tumor cells by 3-bromoacetyl-amino benzoylurea, a new cancericidal compound. Cancer Res., 58, 2126-2133 (1998).
7. Roboz, J., Deng, L., Ma, L. and Holland, J. F. Investigation of suramin-albumin binding by electrospray mass spectrometry. Rapid Commun. Mass Spectrom. 12, 1319-1322 (1998). 
8. Weigand, M., Hartung, G., Roboz, J., Sieger, S., Wolf, M., Schrenk, H. and Frei, E. Mode of action of methotrexate-albumin in MTX-sensitive CCRF-CEM cells and activity against an MTX-resistant clone. Anti-cancer Drug Design, 16, 227-237 (2001). 
9. Lehrer, S., Roboz, J., Ding, H., Zhao, S., Diamond, E. Holland, J.F., Stone, N., Droller, M. and Stock, R. A 17.5 kDa protein is increased in the serum of men with early stage prostate cancer. Brit. J. Urology, International. 92, 223-225 (2003). 
10. Roboz, J., Mass spectrometry in diagnostic oncoproteomics. Cancer Investigation, 23, 465-478 (2005).

Selected Past Achievements

Early diagnosis and monitoring of transplanted human malignant mesothelioma by the determination of serum hyaluronic acid using size exclusion high performance liquid chromatography (3);
Development of a novel mass spectrometric technique for the diagnosis and monitoring of invasive candidiasis (4);
Methodology for the on-line buffer removal and fraction selection to enable gradient capillary high performance liquid chromatography prior to electrospray mass spectrometry of peptides and proteins (5);
A study of the inhibition of microtubule assembly in tumor cells by 3-bromoacetyl-amino benzoylurea, a new cancericidal compound (6).