Polycystic Kidney Disease Research Program

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Recognition and Publications

Wilson, S.J., Amsler, K., Hyink, D., Burrow, C.R Wilson, P.D. Inhibition of HER-2(neu/ErbB2) restores normal  function and structure to  polycystic kidney disease (PKD) epithelia. BBA Molecular Basis of Disease, 1762: 647-655,  2006.

Polgar, K., Burrow, C.R., Hyink, D., Fernandez, H., Thornton, K., Li, X, Gusella, G.L., Wilson, P.D., Disruption polycystin-1 function interferes with  branching morphogenesis of the ureteric bud in developing mouse kidneys. Dev Biol  286:16-30, 2005.

Battini, L., Fedorova E., Macip, S., Li,X., Wilson,P.D., Gusella, G.L. Knockdown of polycystin-1 by lentiviral-mediated expression of small interference RNA  confers anoikis resistance to MDCK cells. JASN In press, 2006.

Rohatgi, R., Greenberg, A., Burrow, C.R., Wilson, P.D., Satlin, L.M. Na Transport in autosomal recessive polycystic kidney disease (ARPKD) cyst lining epithelial cells. JASN 14: 827-836, 2003.

Wilson, P.D. Molecular and cellular aspects of polycystic kidney disease. New Engl. J. Med.;350: 151-164, 2004.

Li, X., Burrow, C.R., Wilson, P.D., Protein kinase X regulates renal epithelia cell function of polycystin-1, the polycystic kidney disease encoded protein. PLOS Medicine submitted 2006.

 

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