Nieto Laboratory

Gold Divider 4Col

Recognition and Publications

2002-2005          Liver Scholar Fellow
2001-2002          ABMRF/The Foundation for Alcohol Research Fellow
2000-2001          Charles H. Revson Fellow in Biomedical Sciences
1997-1998          Plan Propio de Formación del Personal Investigador
                           Fellow (University of Granada, Spain)
1993                   Extraordinary Award for B.Sc. and M.S., Class 1991

Urtasun R, Cubero FJ, Vera M, Nieto N. Reactive nitrogen species switch on early extracellular matrix remodeling via induction of MMP1 and TNFalpha. Gastroenterology. 2009; 136(4): 1410-22, e1-4.

Cubero FJ, Nieto N. Ethanol and arachidonic acid synergize to activate Kupffer cells and modulate the fibrogenic response via TNF alpha, reduced glutathione, and TGFß-dependent mechanisms. Hepatology 2008; 48(6): 2027-39.

Nieto N. Ethanol and fish oil induce NFkappaB transactivation of the COL1A2 promoter through lipid peroxidation-driven activation of the PKC-PI3K-Akt pathway. Hepatology 2007; 45(6): 1433-45.

Nieto N. Oxidative-stress and IL-6 mediate the fibrogenic effects of Kupffer cells on stellate cells. Hepatology 2006; 44(6):1487-501.

Carmiel-Haggai M, Cederbaum AI, Nieto N. A high-fat diet leads to the progression of non-alcoholic fatty liver disease in obese rats. FASEB J 2005; 19(1):136-8.

Nieto N, Cederbaum AI. S-adenosylmethionine blocks collagen I production by preventing transforming growth factor-ß induction of the COL1A2 promoter. J Biol Chem 2005; 280(35): 30963-74.

Gong P, Cederbaum AI, Nieto N. Heme oxygenase-1 protects HepG2 cells against cytochrome P450 2E1-dependent toxicity. Free Radic Biol Med 2004; 36(3): 307-18.

Gong P, Cederbaum AI, Nieto N. The liver-selective nitric oxide donor O2-vinyl 1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate (V-PYRRO/NO) protects HepG2 cells against cytochrome P450 2E1-dependent toxicity. Mol Pharmacol 2004; 65(1): 130-8.

Nieto N, Mari M, Cederbaum AI. Cytochrome P450 2E1 responsiveness in the promoter of glutamate-cysteine ligase catalytic subunit. Hepatology 2003; 37(1): 96-106.

Nieto N, Cederbaum AI. Increased Sp1-dependent transactivation of the LAM?1 promoter in hepatic stellate cells co-cultured with HepG2 cells overexpressing cytochrome P450 2E1. J Biol Chem 2003; 278(17): 15360-15372.

Carmiel-Haggai M, Cederbaum AI, Nieto N. Binge ethanol exposure increases liver injury in obese rats. Gastroenterology 2003; 125(6): 1818-33.

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