Amin R. Mazloom, Ph.D.
Postdoctoral Fellow
Department of Pharmacology and Systems Therapeutics
E-mail: amin.mazloom@mssm.edu

Mailing Address

One Gustave L. Levy Place, Box 1215, New York, NY 10029

Training and Education

Ph.D. (2008) Computer Science and Engineering, University of Texas at Arlington
M.S. (2004) Computer Science and Engineering, University of Texas at Arlington
B.S. (1998) Computer Software Engineering, Azad University of Tehran

Research Interests

My current research focus is in the interdisciplinary field of computational systems biology. More specifically, on building computational models to capture physicochemical behavior of biological processes, then further integrating these models to study the dynamics of an objective complex biological system. Stochastic discrete event-based simulation is the framework for my modeling and simulation practices. In this framework we abstract a pathway as a network of stochastic events. The dynamics of such network evolves through the execution of individual events in a discrete time domain. Each network might cross-talk to the other networks or positively/negatively feeds back to itself.

With an in-silico version of a pathway we can perceive the effect of external and internal signals on that pathway. I have applied the above approach in studying the plasticity of cardiac myocytes as well as transcriptional effect of insulin in cardiac myocytes.

As my alternative research interest, I have worked on some of the hot topics in wireless networks including: QoS constrained scheduling and multimedia (MPEG-4) streaming over wireless mobile networks (i.e. HDR and CDMA2000).

Also I worked on all-optical core mesh networks design and high performance OBS based switching/scheduling in core optical networks.

Publications and Presentations

Amin R. Mazloom, Kalyan Basu, and Sajal K. Das, A Random Walk Modelling Approach for Passive Metabolic Pathways in Gram-Negative Bacteria, IEEE Symp. on Comp. Intel. in Bioinfo. and Comp. Biol. (CIBCB), 2006,pp.1-8.

Amin R. Mazloom, Kalyan Basu and Sajal K. Das, A Random Walk Modeling Approach for Modeling Glucose uptake in Gram-Negative Bacteria, presented at Dallas Bioinformatics Workshop 2006.

Amin R. Mazloom, Kalyan Basu, Subhrangsu S. Mandal, Mehran Sorourian and Sajal Das, DNA Sites Buried in Nucleosome become Accessible at Room Temperature: A Discrete-Event-Simulation based Modeling Approach, Int. Symp. on Bioinfo. Res. and App. (ISBRA), 2007, pp. 601-614.

Samik Ghosh, Amin R. Mazloom, Preetam Ghosh, Kalyan Basu and Sajal K Das, Connecting the Dots: An Integrated Database for Studying Cellular Dynamics, Eighth Int. Conf. on Systems Biology (ICSB), Oct 1-6, CA, USA. 2007.

Awards and Affiliations

Stem Doctoral Fellowship, University of Texas at Arlington (2007)
Member of International Society of Computational Biology (ISCB)
Member of International Society of System Biology (ISSB)