The Institute for Personalized Medicine at Mount Sinai

Institute for Personalized Medicine at Mount Sinai Clinical
The Institute of Personalized Medicine at Mount Sinai Clinical
Molecular Risk Factors of Thrombosis

APOE

  • Objective: To assess the risk for coronary artery disease
  • Description: Detect genetic variants in the apolipoprotein E (ApoE) gene (2, 3, 4 alleles) that affect lipid metabolism and risk for cardiovascular disease
  • Performing Lab: Performing Lab: Molecular Pathology
    Direct inquiries to Dr. David Y. Zhang (212)659-8173
  • Specimen requirements: Specimen requirements: One (1) lavender top (EDTA) tube (4ml) from peripheral blood

PAI-1 (4G/5G)

  • Objective: To assess the risk for coronary artery disease
  • Description: Detect genetic variants in the (plasminogen activator inhibitor type 1) gene 4G/5G alleles) that the risk for cardiovascular disease and myocardial infarction
  • Performing Lab: Molecular Pathology
    Direct inquiries to Dr. David Y. Zhang (212)659-8173
  • Specimen requirements: Specimen requirements: One (1) lavender top (EDTA) tube (4ml) from peripheral blood

Factor II (G20210A), Factor V Leiden Mutation

  • Objective: To assess the risk of developing deep vein thrombosis and other unusual site thrombosis
  • Description: Detect genetic variants in coagulation factors Factor II gene (G20210A) and Factor V gene ((R506Q)
  • Performing Lab: Molecular Pathology
    Direct inquiries to Dr. David Y. Zhang (212)659-8173
  • Specimen requirements: Specimen requirements: one (1) lavender top (EDTA) tube (4ml) from peripheral blood

MTHFR

  • Objective: To assess the risk of develop venous thrombosis, coronary artery disease, neural tube defects, mental retardation, etc.
  • Description: Detect genetic variants in Methylenetetrahydrofolate reductase (MTHFR) gene (C677T and A1298C mutations)
  • Performing Lab: Molecular Pathology
    Direct inquiries to Dr. David Y. Zhang (212)659-8173
  • Specimen requirements: One (1) lavender top (EDTA) tube (4ml) from peripheral blood
Mount Sinai School of Medicine
(800) MD-SINAI (800) 637-4624

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