Born in Chennai, India, Prakash Krishnan, M.D. had his early education at Xaverian High School, Brooklyn, New York and Fordham University, Bronx, New York. He graduated from Rajah Muthiah Medical College in India, and completed his medical residency at St. Vincent's Medical Center, New York, and cardiology fellowship at the Ochsner Clinic Foundation in Louisiana. He finished his Interventional cardiology fellowship at Mount Sinai Medical Center, New York, and received further advanced training in Endovascular Intervention and Vascular Medicine at North Central Heart Institute/Heart Hospital of South Dakota. Dr. Krishnan has been mentored throughout his training by some of the most renowned interventional cardiologists and endovascular interventionalists in the world. At the Ochsner Clinic Foundation he received his basic training in diagnostic coronary and peripheral angiography under the tutelage of Christopher J. White, M.D. and Stephen, R. Ramee, M.D. At The Mount Sinai Medical Center, Samin K. Sharma, M.D. mentored him in the art of Complex Coronary angioplasty and intervention. His training as an endovascular interventionalist was completed under the guidance of Dr. J. Michael Bacharach, M.D., M.P.H. He returned to New York in 2004 and is the Director of Endovascular Intervention and a staff Interventional Cardiologist in the Cardiac Catheterization Laboratory at Mount Sinai Heart.

Dr. Krishnan performs both coronary and endovascular interventions in the Cardiac Catheterization Laboratory. In a short period of time he has performed over 1,500 procedures (including diagnostic coronary and peripheral angiograms and complex coronary and endovascular interventions) with more than a 99 percent success rate and less than one percent major complication rate. Dr. Krishnan is one of the leaders in New York City in Endovascular Intervention. He is an expert at catheter based vascular therapy techniques with balloon angioplasty, stenting, atherectomy, cryoplasty, and laser of all vascular beds including the carotid, vertebral, subclavian, renal mesenteric, iliac, femoral and tibial arteries.

Dr. Krishnan has maintained a standard of excellence throughout his career. He has received numerous academic medals in medical school, including the "Intern of the Year","Chief Medical Resident", and "Chief Cardiology Fellow" in his residency and fellowship respectively. He has published in peer review journals focusing in the areas of intermittent claudication and distal embolic protection, and is active in many clinical trials; most recently the NIH sponsored CORAL Trial (Cardiovascular Outcomes with Renal Atherosclerotic Lesions). In addition he has been an invited moderator to numerous meetings and has performed live cases demonstrating the most current and safe techniques of endovascular intervention.

A patient advocate, Dr. Krishnan has dedicated his time in educating both patients and primary care physicians about peripheral arterial and coronary artery disease. He has been featured in WB 11 news, Business Wire, and Crain's New York Business.