Specialty	Neurology
Clinical Interests	Dystonia
	Tremors
	Movement Disorders
	Huntington Disease
	Gait Disorders
	Tic Disorders
	Botox Injection
	Deep Brain Stimulation
	Parkinson's Disease
Languages	English
	Italian
Gender	Male
E-mail	michele.tagliati@mssm.edu
Education and Training	MD, Universita Di Roma
	Residency, Neurology, Mount Sinai Hospital
	Internship, Internal Medicine, Mount Sinai School of Medicine
	Residency, Neurology, Universita Di Roma
	Fellowship, Neuro-Aids, Mount Sinai Hospital
	Fellowship, Movement Disorder, Beth Israel Medical Center
Awards	2005 DMRF Presidential Award
	2000 Singer/Hellman Research Award
	1998 American Academy of Neurology Resident Award
	1995 American Academy of Clinical Neurophysiology Fellowship
	1993 Postdoctoral Research Fellowship Aaron Diamond Foundation
	1990 CNR-NATO Advanced Fellowship for Research Abroad

Dr. Michele Tagliati is Associate Professor of Neurology at Mount Sinai School of Medicine and Director of the Parkinson's Disease Center. He earned his M.D. from the University of Rome in 1986, where he also completed a residency in neurology and a fellowship in clinical neurophysiology. In 1993, Dr. Tagliati moved to New York, where he completed a second neurology residency at Mount Sinai. Upon completion of residency, Dr. Tagliati joined the movement disorders group at Beth Israel Medical Center in New York for five years. After serving as a faculty member at Albert Einstein College of Medicine, he returned to Mount Sinai to become Division Chief of Movement Disorders. Dr. Tagliati is a diplomat of the American Board of Psychiatry and Neurology.

Dr. Tagliati's contribution to the field of Movement Disorders is extensive. He is a leader in the field of deep-brain stimulation for Parkinson's disease and dystonia and currently serves as teaching faculty at the American Academy of Neurology and the Movement Disorders Society. Dr. Tagliati has published more than 50 peer-reviewed articles. He is an appointed officer of the Movement Disorders Society, an active member of the American Academy of Neurology, Scientific Advisor of the Parkinson Alliance and serves in the Scientific Board of the Bachmann-Strauss Foundation, in the Task Force for DBS in Dystonia of the Movement Disorder Society and the Guideline Project on Deep Brain Stimulation and Dystonia of the American Academy of Neurology.

Dr. Tagliati's clinical interests include primarily Parkinson's disease and related movement disorders (e.g. dystonia, tics, chorea, myoclonus). Dr. Tagliati utilizes both established pharmacological approaches and novel treatments, including deep brain stimulation and botulinum toxin injections. Cutting-edge therapeutic strategies, if clinically indicated, are also offered through the participation in available clinical trials.

Education and Training	MD, Universita Di Roma
	Residency, Neurology, Mount Sinai Hospital
	Internship, Internal Medicine, Mount Sinai School of Medicine
	Residency, Neurology, Universita Di Roma
	Fellowship, Neuro-Aids, Mount Sinai Hospital
	Fellowship, Movement Disorder, Beth Israel Medical Center
Board Certification	Neurology

Specialty	Neurology
Clinical Interests	Dystonia
	Tremors
	Movement Disorders
	Huntington Disease
	Gait Disorders
	Tic Disorders
	Botox Injection
	Deep Brain Stimulation
	Parkinson's Disease
Languages	English
	Italian
Board Certification	Neurology

Deep Brain Stimulation for Movement Disorders
1. Effects of Unilateral and Bilateral DBS on mood in patients with parkinson's disease.

2. New parameters of stimulation for DBS as a Treatment of Dystonia.

3. Study Of Long-Term Outcomes And Complications of DBS for Movement Disorders.

4. Cortical-Subcortical Interaction in PD and Normal Speech with and without DBS

5. Low Frequency Deep Brain Stimulation for Gait Dysfunction in Parkinson's disease

Ongoing Clinical Trials
1. Evaluation of Bilateral Stimulation of STN using Libra Implantable Brain Stimulation System.

2. Extended Observation Study to Assess the Safety and Efficacy of Idiopathic Parkinson's Disease Patients Treated with CERE-120.

Completed Clinical Trials:
1. Multicenter, Open-Label Trial To Assess Subject Preference Of Parcopa, Carbidopa/Levodopa Orally Disintegrating Tablets, Compared To Conventional Carbidopa/Levodopa Tablets In Subjects With Stable Parkinson's Disease.

2. Feasibility Study on the Use of a Parkinson's disease Symptoms Diary For The Planned Phase III Studies With Sarizotan (EMR 62-225).

3. A double-blind, placebo controlled, multicenter, multinational Phase III study to evaluate the safety and efficacy of Sarizotan HCl 1 mg b.i.d. in patients with Parkinson's disease suffering from treatment associated dyskinesias (PADDY-2).

4. An international, multi-center, randomized, double-blind, parallel group, active controlled Study to evaluate onset of dyskinesias in patients taking levodopa/carbidopa and entacapone (Stalevo (r)), compared to those taking a traditional levodopa/carbidopa product [STRIDE-PD].

5. Study of the safety, tolerability and efficacy of Spheramine(R) implanted bilaterally into the postcommissural putamen of patients with advanced Parkinson's disease.

6. Randomized Start Study to Assess Rasagiline as Therapy in PD.

7. Medtronic 1629 usability study. Principal Investigator: M.Tagliati. Sponsor Medtronic. Approval dates: 4/1/07-3/31/08. Effort 5%.

8. Study of CERE-120 to Assess the Safety of Bilateral Delivery.

Tagliati M, Shils JL, Sun C, Alterman RL. Deep Brain Stimulation for Dystonia . Expert review of Medical Devices 2004; 1: 33-41.

Kedia S, Moro E, Tagliati M, Lang AE, Kumar R. Emergence of Restless Legs Syndrome (RLS) during subthalamic stimulation for Parkinson's disease . Neurology 2004; 63: 2410-2412.

Okun M, Tagliati M, Pourfar M, Fernandez H, Rodriguez RL, Alterman RL, Foote KL. Management of Referred DBS Failures: A Retrospective Analysis From Two Movement Disorders Centers. Arch Neurol 2005; 62: 1250-1255.

Alterman R, Shils J, Miravite J, Tagliati M. A lower Stimulation Frequency Can Enhance Tolerability and Efficacy of Pallidal Deep Brain Stimulation for Dystonia . Movement Disorders 2007; 22: 366-368.

Alterman RL, Tagliati M. Deep brain stimulation for torsion dystonia in children . Childs Nerv Syst 2007; 23: 1033-1040.

Alterman RL, Miravite J, Weisz D, Shils JL, Bressman S, Tagliati M. Sixty Hertz Pallidal DBS for Primary Torsion Dystonia. Neurology 2007; 69: 681-698.

Isaias IU, Alterman R, Tagliati M. Outcome Predictors for DBS in Primary Dystonia: The Role of Disease Duration. Brain 2008; 131: 1895-1902.

Tagliati M. Fine tuning gait in Parkinson's disease. Neurology 2008; 71: 76-77.

Stocchi F, Tagliati M, Olanow CW. Treatment of Levodopa-Induced Motor Complications . Movement Disorders 2008; 23(Suppl 3): S599-S612.

Halbig T, Tse W, Frisina PG, Baker BR, Hollander E, Shapiro H, Tagliati M, Olanow CW. Subthalamic Deep Brain Stimulation and Impulsivity in Parkinson's disease. Eur J Neurology 2009; In Press.

Isaias IU, Alterman R, Tagliati M. Deep Brain Stimulation for Primary Dystonia: Long-term Outcomes. Arch Neurol 2009; In press.