Find a Faculty

Gold Divider 4Col
Physician Photo

Rong-fang Wang

ASSOCIATE PROFESSOR  Ophthalmology

Overview

Gender Female
E-mail rong-fang.wang@mssm.edu
Education and Training M.S., Eye and ENT Hospital Shanghai Medical University
  M.D., Shanghai Medical University
  Fellowship, The Mount Sinai Medical Center
  Fellowship, New York Eye and Ear Infirmary
  Resident, Gau Su Province People's Hospital
  Internship, Hua Shan Hospital, Shanghai Medical University

Dr. Wang's major research field is on glaucoma pharmacology. Her studies encompass the development new anti-glaucoma drugs and elucidation of the mechanism of action of ocular hypotensive agents, testing different kinds of new potential drugs in normal and glaucomatous monkeys. This is very important procedure to predict a clinical response of new potential drugs in glaucoma patients.

Currently, lowering intraocular pressure (IOP) is the only established effective treatment for glaucoma patients. Medications are usually considered the first line treatment for glaucoma. In the past decade, several experimental compounds investigated in the glaucoma laboratory have been released for clinical treatment of glaucoma. These are Trusopt, a topical carbonic anhydrase inhibitor; Xalatan, a prostaglandin F2? analog; Alphagan, a ?2-adrenergic agonist. These new drugs have greatly enhanced the options for the medical treatment of glaucoma.

Dr. Wang received her M.S. in Genetics of Ophthalmology in 1982 and her M.D. from Faculty of Medicine in 1969, both from Shanghai Medical University. Her M.S. thesis received achievement award from the Ministry of National Health of The People's Republic of China. Before she arrived in the United States, she was an Attending Doctor and Assistant Professor at Eye and ENT Hospital of Shanghai Medical University.

When she arrived in New York, Dr. Wang was a Clinical Research Fellow in Glaucoma at the New York Eye and Ear Infirmary. She has joined Mount Sinai in the department of ophthalmology since 1986.

Dr. Wang is a productive research scientist. Many of her work have been published in Archives of ophthalmology, which ranks first among clinical ophthalmology with the greatest impact in over 95 countries.

Dr. Wang has given invited lectures on the international conference in China. Currently, she in on the editorial board of Journal of Chinese Ophthalmology and Otolaryngology.

Training

Education and Training M.S., Eye and ENT Hospital Shanghai Medical University
  M.D., Shanghai Medical University
  Fellowship, The Mount Sinai Medical Center
  Fellowship, New York Eye and Ear Infirmary
  Resident, Gau Su Province People's Hospital
  Internship, Hua Shan Hospital, Shanghai Medical University

Research

Searching for the new classes of anti-glaucoma drugs that are different from currently clinical used drugs.

Glaucoma is a progressive optic neuropathy and not a pressure disease. Lowering IOP provides only partial solution to treating this blinding disease. Thus, searching for a new therapeutic way that can provide neuroprotection or neurorepair is our target.

Publications

Wang RF, Lee PY, Mittag TW, Podos SM, Serle JB. Effect of 5-methylurapidil, an I?1A-adrenergic antagonist and 5-hydroxytryptamine1a (serotonin) agonist, on aqueous humor dynamics in monkeys. Curr Eye Res 1997 Aug; 16(8): 769-75.


Wang RF, Lee PY, Mittag TW, Podos SM, Serle JB, Becker B. Effect of 8-iso prostaglandin E2 on aqueous humor dynamics in monkeys. Arch Ophthalmol 1998 Sep; 116(9): 1213-6.


Wang RF, Schumer RA, Serle JB, Podos SM. A comparison of argon laser and diode laser photocoagulation of trabecular meshwork to produce the glaucoma monkey model. J Glaucoma 1998 Feb; 7(1): 45-9.


Wang RF, Podos SM, Serle JB, Mittag TW, Ventosa F, Becker B. Ventosa F, Becker B. Effect of latanoprost or 8-iso prostaglandin E2 alone and in combination on intraocular pressure in glaucomatous monkey eyes. Arch Ophthalmol 2000 Jan; 118(1): 74-7.


Wang RF, Serle JB, Gagliuso DJ, Podos SM. Comparison of ocular hypotensive effect of brimonidine, dorzolamide, latanoprost or artificial tears added to timolol in glaucomatous monkey eyes. J Glaucoma 2000 Dec; 9(62): 458-62.


Serle JB, Wang RF, Mittag TW, Shen F, Podos SM. Effect of pilocarpine 4% in combination with latanoprost 0.005% or 8-iso prostaglandin E2 0.1% on intraocular pressure in laser-induced glaucomatous monkey eyes. J Glaucoma 2001 Jun; 10(3): 215-9.


Chien FY, Wang RF, Mittag TW, Podos SM. Effect of WIN 55212-2, a cannabinoid receptor agonist, on aqueous humor dynamics in monkeys. Arch Ophthalmol 2003 Jan; 121(1): 87-90.


Tian B, Wang RF, Podos SM, Kaufman PL. Effects of topical H-7 on outflow facility, intraocular pressure, and corneal thickness in monkeys. Arch Ophthalmol 2004 Aug; 122(8): 1171-7.


Gagliuso DJ, Wang RF, Mittag TW, Podos SM. Additivity of bimatoprost or travoprost to latanoprost in glaucomatous monkeys eyes. Arch Ophthalmol 2004 Sep; 122(9): 1342-7.


Wang RF, Podos SM, Mittag TW, Yokoyoma T. Effect of CS-088, an angiotensin AT1 receptor antagonist, on intraocular pressure in glaucomatous monkey eyes. Exp Eye Res 2005 May; 80(5): 629-32.


Institutes, Centers, Programs and Laboratories

The Mount Sinai Medical Center is home to an extensive array of top-notch research centers and laboratories, where scientists and researchers work to translate the rapid advances in basic science into the innovative patient care for which we are known.

Clinical Trials

Participating in Mount Sinai’s clinical trials allows you to take advantage of innovative treatments as we work together to advance the future of medicine.

(800) MD-SINAI (800) 637-4624

Visit Mount Sinai Queens