Gender	Male
E-mail	defeng.wu@mssm.edu
Education and Training	Ph.D., Cancer Institute, Beijing Union Medical College
	M.S., Cancer Institute, Beijing Union Medical College
	B.S., Fujian Medical College
	Fellowship, Mount Sinai School of Medicine, City University
	Residency, First Hospital Affiliated with Fujian Medical College, Fuzhou Hospital for Infectious Diseases
Awards	1988 The Second Prize of Advantage Award National Health Science and Technology, China
	1982 The Second Prize of Chinese National Natural Science Award

Education and Training	Ph.D., Cancer Institute, Beijing Union Medical College
	M.S., Cancer Institute, Beijing Union Medical College
	B.S., Fujian Medical College
	Fellowship, Mount Sinai School of Medicine, City University
	Residency, First Hospital Affiliated with Fujian Medical College, Fuzhou Hospital for Infectious Diseases

Wu D, Cederbaum AI. Ethanol and arachidonic acid produce toxicity in hepatocytes from pyrazole-treated rats with high levels of CYP2E1. Mol Cell Biochem 2000 Jan; 204(1-2): 157-67.

Wu D, Cederbaum AI. Removal of glutathione produces apoptosis and necrosis in HepG2 cells overexpressing CYP2E1. Alcohol Clin Exp Res 2001 Apr; 25(4): 619-28.

Wu D, Cederbaum AI. Sodium salicylate increases CYP2E1 levels and enhances arachidonic acid toxicity in HepG2 cells and cultured rat hepatocytes. Mol Pharmacol 2001 Apr; 59(4): 795-805.

Cederbaum AI, Wu D, Mari M , Bai J . CYP2E1-dependent toxicity and oxidative stress in HepG2 cells. Free Radic Biol Med 2001 Dec 15; 31(12): 1539-43.

Mari M, Wu D, Nieto N, Cederbaum AI. CYP2E1-dependent toxicity and up-regulation of antioxidant genes. J Biomed Sci 2001 Jan-Feb; 8(1): 52-8.

Wu D, Cederbaum AI. Cyclosporine A protects against arachidonic acid toxicity in rat hepatocytes: role of CYP2E1 and mitochondria. Hepatology 2002 Jun; 35(2): 1420-30.

Wu D, Cederbaum AI. Role of p38 MAPK in CYP2E1-dependent arachidonic acid toxicity. J Biol Chem 2003 Jan 10; 278(2): 1115-24.

Wu D, Cederbaum A. Glutathione depletion in CYP2E1-expressing liver cells induces toxicity due to the activation of p38 mitogen-activated protein kinase and reduction of nuclear factor-kappaB DNA binding activity. Mol Pharmacol 2004 Sep; 66(3): 749-760.

Wu D, Cederbaum AI. Oxidative stress mediated toxicity exerted by ethanol-inducible CYP2E1. Toxicol Appl Pharmacol 2005 Sep 1; 207(2 Suppl): 70-6.

Wu D, Cederbaum AI. Opposite action of S-adenosyl methionine and its metabolites on CYP2E1-mediated toxicity in pyrazole-induced rat hepatocytes and HepG2 E47 cells. Am J Physiol Gastrointest Liver Physiol 2006 Apr; 290(4): G674-84.