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Erin Hazlett

ASSOCIATE PROFESSOR  Psychiatry

Overview

Gender Female
E-mail erin.hazlett@mssm.edu
Education and Training B.A., University of California
  M.A., University of Southern California
  Ph.D., University of Southern California

Dr. Hazlett is Associate Professor and Associate Director of the Neuroscience PET Lab. She received her Ph.D. in Psychology from the University of Southern California and completed a postdoctoral fellowship in the Department of Psychiatry at Mount Sinai School of Medicine. She is the Principal Investigator of grants from the National Institutes of Mental Health (NIMH) and has received both a Young Investigator and an Independent Investigator Award from the National Alliance for Research on Schizophrenia and Depression (NARSAD). Her work was featured on the cover of two international journals (Biological Psychiatry (2005 v58) and the American Journal of Psychiatry (1999 v156). Dr. Hazlett is a member of the Association for Psychological Research and the Society of Psychophysiological Research.

Training

Education and Training B.A., University of California
  M.A., University of Southern California
  Ph.D., University of Southern California

Research

Specific Clinical/Research Interests: Imaging, Schizophrenia and Other Psychiatri c Disorders, Anatomy and Neuroanatomy, Neurophysiology

Current Students: 2 students from Psychology MA program at NYU, 2 PhD students in psychology from Queen's College

Postdoctoral Fellows: 2

Research Personnel: 2 research assistants

Dr. Hazlett's research uses brain imaging (functional and structural) and psychophysiology (skin conductance and startle eyeblink responses) to examine the neural circuitry involved in attention and emotion processing. She examines how individuals with schizophrenia-spectrum disorders characterized by emotion and attention dysfunction differ from healthy individuals in terms of psychophysiological responses (e.g., frontal lobe activation and startle eyeblink magnitude) during cognitive processing. Positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) are used to examine the brain's function while structural MRI scans are used to see the brain's structure. Psychophysiological measures are also used in Dr. Hazlett's research to study the time course and magnitude of attentional and emotional processing. She has published PET, fMRI, structural MRI, and psychophysiological studies on schizophrenia, autism, personality disorders (borderline and schizotypal) and healthy aging. Dr. Hazlett's most recent study funded by NIMH uses these biological measures to better understand emotion processing in healthy individuals and individuals with emotion dysregulation and personality disorders (borderline personality disorder and schizotypal personality disorder).

Publications

Hazlett EA, Dawson ME, Schell AM, Nuechterlein KH. Probing attentional dysfunctions in schizophrenia: Startle modification during a continuous performance test [PMID: 18282203]. Psychophysiology 2008; 45: 632-642.


Hazlett EA, Buchsbaum MS, Haznedar MM, Newmark RE, Goldstein KE, Zelmanova Y, Glanton CF, Torosjan Y, New AS, Lo JN, Mitropoulou V, Siever LJ. Cortical gray and white matter volume in unmedicated schizotypal and schizophrenia patients [PMID: 18272348]. Schizophrenia Research 2008; 101: 111-123.


Hazlett EA, Byne W, Mitsis EM, Brickman AM, Newmark R, Haznedar MM, Knatz DT, Chen AD, Buchsbaum MS. Age and sex differences in glucose metabolism of the frontal lobe and cingulate gyrus (Epub ahead of print) [PMID: 19027195]. Neurobiology of Aging 2008;.


Hazlett EA, Buchsbaum MS, Zhang J, Newmark RE, Glanton CF, Zelmanova Y, Haznedar MM, Chu KW, Nenadic I, Kemether EM, Tang CY, New AS, Siever LJ. Frontal-striatal-thalamic mediodorsal nucleus dysfunction in schizophrenia-spectrum patients during sensorimotor gating [PMID: 18588988]. NeuroImage 2008; 42: 1164-1177.


Byne W, Hazlett EA, Buchsbaum MS, Kemether E. The thalamus and schizophrenia: Current status of research (Epub ahead of print) [PMID: 18604544]. Acta Neuropathologica 2008;.


Buchsbaum MS, Hazlett EA. Functional brain imaging studies in dementia . In: Charney DS, Nestler E, editors. Neurobiology of Mental Illness. Third edition. (2008). Oxford, Oxford University Press; pp849-862.


Hazlett EA, Romero MJ, Haznedar MM, New AS, Goldstein KE, Newmark RE, Siever LJ, Buchsbaum MS. Deficient attentional modulation of startle eye-blink is associated with symptom severity in the schizophrenia spectrum. Schizophrenia Research 2007; 93: 288-293.


Hazlett EA, Speiser LJ, Goodman M, Roy M, Carrizal M, Wynn JK, Williams WC, Romero M, Minzenberg MJ, Siever LJ, New AS. Exaggerated affect-modulated startle during unpleasant stimuli in borderline personality disorder [This article was featured on the National Institute of Mental Health website under . Biological Psychiatry 2007; 62: 250-255.


New AS, Hazlett EA, Buchsbaum MS, Goodman M, Mitelman SA, Newmark R, Trisdorfer R, Haznedar MM, Koenigsberg HW, Flory J, Siever LJ. Amygdala-prefrontal disconnection in borderline personality disorder. Neuropsychopharmacology 2007; 32: 1629-1640.


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