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Yongchao Ge

ASSISTANT PROFESSOR  Neurology

Overview

Gender Male
E-mail yongchao.ge@mssm.edu
Education and Training Ph.D., University of California at Berkeley
  M.E., Peking University
  B.S., Beijing Normal University

Training

Education and Training Ph.D., University of California at Berkeley
  M.E., Peking University
  B.S., Beijing Normal University

Research

Research Interests

His research focuses on developments of statistical methods and tools for biological applications, especially in molecular genetics area. The emphasis is on understanding the massive data generated in functional genomics as a statistician. For example, in microarray data, he has done extensive work on finding differentially expressed genes, especially on false discovery rates and recently false discovery proportion for multiple testing problems. He is interested in many areas of microarrays: experimental design, normalization, clustering analysis and how to connect microarray data with clinical data and other biological data: sequence information, real time PCR, functional annotation, flow cytometry and proteomics data.

Publications

Giordano J, Ge Y, Warburton PE, Abrusan G, Benson G, Gelfand Y. Evolutionary History of Mammalian Transposons Determined by Genome-wide Defragmentation. PLoS Computational Biology 2007;.


Ge Y, Speed TP, Tseng CH, Sealfon SC. A Holm-type procedure controlling the false discovery rate. Statistics & Probability Letters 2007;.


Chu TT, Fink MY, Mong JA, Sealfon SC, Auger AP, Ge Y, John G. Effective use of microarrays in neuroendocrine research. Journal Of Neuroendocrinology 2007; 19(3): 145-161.


Gonzalez-Maeso J, Weisstaub NV, Zhou M, Chan P, Ivic L, Gingrich JA, Lira A, Bradley-Moore M, Ge Y, Zhou Q, Sealfon SC, Ang R. Hallucinogens recruit specific cortical 5-HT(2A) receptor-mediated signaling pathways to affect behavior. Neuron 2007; 53(3): 439-452.


Ruf F, Hayot F, Park MJ, Sealfon SC, Roysam B, Ge Y, Lin G. Mixed Analog/Digital Gonadotrope Biosynthetic Response to Gonadotropin Releasing Hormone. Journal of Biological Chemistry 2006; 81(41): 30967-30978.


Ge Y, Speed TP, Sealfon SC, Li X. An upper confidence bound for the false discovery proportion. Proceedings of the American Statistical Association, Statistical Computing Section [CD-ROM] 2005;: 2093-2100.


Gentleman RC, Zhang J, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irrizary R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang YH, Carey VJ. Bioconductor: open software development for computational biology and bioinformatics. Genome Biology 2004; 5(10): R80.


Ge Y, Speed TP, Dudoit S. Resampling-based multiple testing for microarray data analysis. Test 2003; 12(1): 1-44 .


Diaz E, Ge Y, Yang YH, Loh KC, Scheiffele P, Okazaki Y, Hayashizaki Y, Speed TP, Ngai J, Serafini TA. Molecular analysis of gene expression in the developing pontocerebellar projection system. Neuron 2002; 36(3): 417-434.


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