Research
Dr. Sung is currently conducting clinical trials of immunotherapy in patients with advanced colorectal and breast cancers using gene transfer therapy. He is also involved in clinical trials of suicide gene therapy and differentiation therapies for colorectal cancer, and anti-angiogenesis therapy for hepatocellular carcinoma.
Dr. Sung actively participates in multi-modality treatment approaches (surgery/radiation/chemotherapy) to cancers of the liver, colon-rectum, carcinoid, pancreas, esophagus, stomach and anal cancers, and is also experienced in regional treatment modalities such as hepatic arterial chemotherapy/chemoembolization and intraperitoneal chemotherapy.
Publications
Sung MW, Yeh HC, Thung SN, Schwartz ME, Mandeli JP, Chen SH, Woo SL C. Intratumoral Adenovirus-Mediated Suicide Gene Therapy for Hepatic Metastases from Colorectal Adenocarcinoma: Results of a Phase I Clinical Trial. Mol Ther 2001; 4: 182.
Sung MW, Chen SH, Thung SN, Zhang DY, Huang TG, Mandeli JP, Woo SL C. Intratumoral Delivery of Adenovirus-Mediated Interleukin-12 Gene in Mice Bearing Metastatic Cancer in the Liver. Hum Gene Ther 2002; 13: 731.
Sung MW, Chen SH, Woo SL C. New Approaches to Gene Therapy for Cancer. In: DeVita VT, Hellman S, Rosenberg SA, editors. Progress in Oncology 2002. Sudbury, Massachusetts, Jones & Bartlett; 2002. pp36-53.